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Image Search Results
Journal: Cell Death Discovery
Article Title: B7-H5 blockade enhances CD8 + T-cell-mediated antitumor immunity in colorectal cancer
doi: 10.1038/s41420-021-00628-4
Figure Lengend Snippet: A Growth curve of MC38 tumors after treatment with monoclonal anti-mouse B7-H5 antibody (B7-H5 mAb) or control IgG. n = 7. The experiments were performed in triplicate. Values are expressed as means (SEMs). ** P < 0.01. B The proportion of CD3 + T and CD8 + T cells in tumor tissues from MC38 tumors after treatment with B7-H5 mAb or control IgG was analyzed by immunofluorescence (original magnification ×200). A representative image was shown. n = 4. The experiments were performed in triplicate. Values are expressed as means (SD). * P < 0.05; ** P < 0.01. C The proportion of CD8 + T cells in the CD45 + T cells of tumor tissues from MC38 tumors after treatment with B7-H5 mAb or control IgG was analyzed by flow cytometry. A representative image was shown. n = 4. The experiments were performed in triplicate.
Article Snippet: Frozen sections from mouse tumor tissues (thickness 5 μm) were blocked with 5% bovine serum albumin for 1 h at 37 °C and stained with
Techniques: Control, Immunofluorescence, Flow Cytometry